Mitotic cell division: Interphase
Posted on : 22-02-2017


The term interphase is derived from Latin word ‘inter’ which means ‘between’ and Greek word ‘phasis’ which means ‘appearance’. It occupies about 90% of the cell cycle and is a period of synthesis and growth, during which the cell roughly doubles in mass but without displaying obvious morphological changes.

Interphase as the name suggests, is the stage between two successive cell divisions during which the cell prepares itself for the process by growing in size and synthesizing new nucleic acids & proteins. Chromosomes appear as thread-like chromatin network.

Stages of Interphase

Interphase consists of the following three sub stages.

G1 or Gap-1 phase: This phase starts immediately after previous cell division. The cell grows in size and there is synthesis of new proteins and RNA which are needed for various metabolic activities of the cell. A non-dividing cell does not proceed beyond G1 phase and is said to be in G0 stage or cease phase.

Interphase, G1 phase, Cell division, mitotic cell dicision, mitosis

S-or Synthetic Phase: During this phase there is synthesis of DNA. And each chromosome is now composed of two sister chromatids.

Interphase, G2 phase, Cell division, mitotic cell dicision, mitosis

G2 or Gap-2 Phase: During this phase there is synthesis of proteins responsible for the formation of spindle fibres. Also the cell grows further in size.

Interphase, S phase, Cell division, mitotic cell dicision, mitosis


In summary the following are the events which take place during interphase

  1. Synthesis of new proteins, DNA and RNA
  2. The nuclear envelope remains intact.
  3. The chromosomes occur in the form of diffused, long, coiled and unclearly visible chromatin fibres.
  4. Due to the accumulation of ribosomal RNA and proteins, the nucleolus reaches its maximum size.
  5. A daughter centrosome is originated near the existing centrosome and consequently an interphase cell has two centrosomes.

  1. Give an outlook of Mitotic cell division.
  2. Write about Mitotic Interphase.
  3. What are the phases included in the mitotic cell division.

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