Posted on : 14-07-2018

Phase I of Glycolysis

This phase of glycolysis is also called as preparatory phase. In this stage, the asymmetric form of glucose is converted into symmetric form of glucose called fructose 1, 6-diphosphate. Two phosphate groups from ATP are taken in this conversion.

Glucose is taken up and phosphorylated by the cells

Glucose molecules easily penetrate the hepatic cells of liver, intestinal mucosa cells and cells of kidney tubules. These cells take up the glucose through active transport. On the other glucose is transported with the help of insulin to other body cells. After the transport of glucose to the cells, it is phosphorylated to form glucose 6-phosphate. This phosphorylation is catalysed by the enzyme glucokinase. It is important to note that this reaction is irreversible.

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