According to the formula,

The average of 'n' multiples of a number =$\frac{\mathrm{Number}\times \left(\mathrm{n}+1\right)}{2}$

∴ n=80, number=4

∴ Required average =$\frac{4\times \left(80+1\right)}{2}=\frac{324}{2}=162$

Hence, Option C is correct.